An antique clock within a drop (I took this using the Olympus E-M5 and Olympus ZD 50mm f/2.0 macro - no Photoshop just cropped and resized - see my blog post on how I did this)
need a macro lens, preferably 1:1 macro (a 5x macro will allow a droplet to almost fill the frame), and use manual focus
off-camera flash with a diffuser +/- white board to act as a reflector and provide fill-in light on the opposite side
tripod, preferably with a macro rail to make focus easier
background and a subject to be visible within the droplet placed behind the droplet
droplets:
dew drops outdoors
try glycerin (“glycerol”) or glycerine and water indoors for a more stable, bigger, droplet
a syringe to drop the droplets
shutter speed at flash sync (or can be slower if you wish ambient light to provide some background details)
remote shutter release or self timer
mirror lockup (not needed on mirrorless cameras obviously)
as using macro distances, aperture of f/8-16 may be needed for the droplet and hopefully will be sufficient to blur the subject behind the droplet
alternatively, shallower depth of field (DOF) can be used if one resorts to focus stacking, this will be more likely needed if one wishes to get multiple droplets in focus